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After 4 weeks: Increase to 5 mg subcutaneously once a week

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While CuZnSOD, MnSOD, and catalase are probably not directly upregulated by Nrf2 (as they do not appear to contain Antioxidant Response Elements in their promoters), they have been reported to be included in the array of enzymes induced by Nrf2 activators

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Typical usage levels in cosmetics are usually low and in the range of 0.015 - 2.3%

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